{"id":157402,"date":"2025-05-01T12:26:55","date_gmt":"2025-05-01T11:26:55","guid":{"rendered":"https:\/\/www.kidneyresearchuk.org\/?post_type=research_grants&#038;p=157402"},"modified":"2026-06-09T10:51:40","modified_gmt":"2026-06-09T09:51:40","slug":"paediatric-rare-hereditary-kidney-diseases","status":"publish","type":"research_grants","link":"https:\/\/www.kidneyresearchuk.org\/research-grants\/paediatric-rare-hereditary-kidney-diseases\/","title":{"rendered":"Paediatric, rare and hereditary kidney diseases"},"content":{"rendered":"\n<h2>\n\t\t\tKey information\t<\/h2>\n<h3>Advancing research in paediatric, rare and hereditary kidney diseases<\/h3>\n<p>We are committed to changing the future for children and families affected by kidney disease. Rare and hereditary kidney conditions are complex and often poorly understood, with many patients waiting years for an accurate diagnosis or access to effective treatments. This funding opportunity aims to accelerate research that tackles these challenges head-on.<\/p>\n<p>Rare kidney diseases &#8211; more than 150 distinct conditions &#8211; collectively affect an estimated 160,000 people in the UK. People living with these conditions account for up to 25% of all dialysis and transplant patients, and more than 60% of children with kidney failure have a rare kidney disease as the underlying cause. Despite many conditions being hereditary, diagnostic delay remains common and the evidence base to support new treatments is often limited.<\/p>\n<p>Our <a href=\"https:\/\/www.kidneyresearchuk.org\/about-us\/policy\/rare-diseases-report\/\">Collectively Common report<\/a> (2025) set out a clear agenda for action. This funding opportunity responds directly to that agenda, supporting high\u2011quality research to improve understanding, reduce progression to kidney failure, and expand treatment options for people affected by these diseases.<\/p>\n<h3>Why focus on paediatric, rare and hereditary kidney diseases?<\/h3>\n<p>Children with kidney disease often face lifelong health challenges that begin early in life and continue for decades. A diagnosis of a rare or hereditary kidney condition can reshape every aspect of a person&#8217;s life, from education and employment to relationships and long\u2011term health. Yet for many of these conditions, the research needed to develop better treatments remains limited or absent.<\/p>\n<p>This funding opportunity is a clear commitment to closing that gap and accelerating progress for children, adults and families affected by rare kidney disease.<\/p>\n\t<h3><strong>Research priorities for applicants <\/strong><\/h3>\n<p>Applications are welcome across a wide range of rare, hereditary and paediatric kidney conditions and methodological approaches. In line with our Collectively Common report, we are particularly interested in research that addresses:<\/p>\n\t\t\t\t\t<a role=\"heading\" aria-level=\"2\" tabindex=\"-1\"  id=\"fl-accordion--label-0\">Population\u2011level\u202fresearch\u202f <\/a>\n\t\t\t\t\t\t\t\t\t\t\t<button type=\"button\" id=\"fl-accordion--icon-0\" aria-expanded=\"false\" aria-controls=\"fl-accordion--panel-0\"><i>Expand<\/i><\/button>\n\t\t\t\t\t<p>Research to strengthen\u202fpopulation\u2011level\u202funderstanding of paediatric kidney disease in the UK, informing service planning, research prioritisation and improved outcomes for children and young people.\u202f\u00a0<\/p>\n\t\t\t\t\t<a role=\"heading\" aria-level=\"2\" tabindex=\"-1\"  id=\"fl-accordion--label-1\">Earlier diagnosis<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<button type=\"button\" id=\"fl-accordion--icon-1\" aria-expanded=\"false\" aria-controls=\"fl-accordion--panel-1\"><i>Expand<\/i><\/button>\n\t\t\t\t\t<ul>\n<li>New diagnostic biomarkers and tools<\/li>\n<li>Screening approaches for high\u2011risk groups and families<\/li>\n<li>Research to reduce diagnostic delay, including in children<\/li>\n<\/ul>\n\t\t\t\t\t<a role=\"heading\" aria-level=\"2\" tabindex=\"-1\"  id=\"fl-accordion--label-2\">Understanding disease progression<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<button type=\"button\" id=\"fl-accordion--icon-2\" aria-expanded=\"false\" aria-controls=\"fl-accordion--panel-2\"><i>Expand<\/i><\/button>\n\t\t\t\t\t<ul>\n<li>Mechanisms driving rare kidney diseases<\/li>\n<li>Natural history and disease trajectories<\/li>\n<li>Predictors of progression and outcomes<\/li>\n<\/ul>\n\t\t\t\t\t<a role=\"heading\" aria-level=\"2\" tabindex=\"-1\"  id=\"fl-accordion--label-3\">New treatments and innovation<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<button type=\"button\" id=\"fl-accordion--icon-3\" aria-expanded=\"false\" aria-controls=\"fl-accordion--panel-3\"><i>Expand<\/i><\/button>\n\t\t\t\t\t<ul>\n<li>Development of targeted therapies<\/li>\n<li>Drug repurposing for rare kidney diseases<\/li>\n<li>Patient\u2011reported outcomes research<\/li>\n<\/ul>\n\t\t\t\t\t<a role=\"heading\" aria-level=\"2\" tabindex=\"-1\"  id=\"fl-accordion--label-4\">Reducing lifelong burden<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<button type=\"button\" id=\"fl-accordion--icon-4\" aria-expanded=\"false\" aria-controls=\"fl-accordion--panel-4\"><i>Expand<\/i><\/button>\n\t\t\t\t\t<ul>\n<li>Quality of life, education and psychosocial impact<\/li>\n<li>Interventions to reduce treatment burden<\/li>\n<li>Long\u2011term outcomes beyond kidney function<\/li>\n<li>Transition from paediatric to adult care<\/li>\n<\/ul>\n\t\t\t\t\t<a role=\"heading\" aria-level=\"2\" tabindex=\"-1\"  id=\"fl-accordion--label-5\">Highlight: Polycystic kidney disease (PKD)<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<button type=\"button\" id=\"fl-accordion--icon-5\" aria-expanded=\"false\" aria-controls=\"fl-accordion--panel-5\"><i>Expand<\/i><\/button>\n\t\t\t\t\t<p>Polycystic kidney disease (PKD) is the most common inherited cause of kidney failure and a major driver of lifelong kidney disease in both children and adults.<\/p>\n<p>As part of this paediatric, rare and hereditary kidney diseases funding opportunity, we particularly welcome applications that address unmet research needs in PKD, including work that aligns with the priority areas outlined above.<\/p>\n<p><strong>Areas of strategic interest for PKD include:<\/strong><\/p>\n<strong>Biomarker and molecular insights<br \/>\n<\/strong>Identification and validation of biomarkers, and improved characterisation of PKD phenotypes, including paediatric presentation, cardiovascular and hepatic involvement, sex differences, and variability in disease progression\n<strong>Preclinical innovation<br \/>\n<\/strong>Development of robust experimental platforms to accelerate therapeutic discovery\n<strong>Integrated data and translational tools<br \/>\n<\/strong>Use of large\u2011scale data, registries and computational approaches to improve disease stratification and outcomes\n<strong>Personalised and preventive care strategies<br \/>\n<\/strong>Development of tailored treatments and early interventions\n<strong>Patient\u2011reported outcomes and lived experience<\/strong><br \/>\nFurther development and refinement of patient\u2011reported outcome measures (PROMs), capturing symptom burden, quality of life and impacts across the life course\n\t<h2>Types of grants available<\/h2>\n<p>We welcome applications submitted through our first main grant round for the following grant types<\/p>\n\t\t\t\t\t<h2 id=\"fl-accordion--label-0\">Research project grants<\/h2>\n\t\t\t\t\t\t\t\t\t\t\t<button type=\"button\" id=\"fl-accordion--icon-0\" aria-expanded=\"false\" aria-controls=\"fl-accordion--panel-0\"><i>Expand<\/i><\/button>\n\t\t\t\t\t<ul>\n<li>Funding available: up to \u00a3300,000<\/li>\n<li>Funding period: maximum of three years, may be spread over a three-year period.<\/li>\n<\/ul>\n\t\t\t\t\t<h2 id=\"fl-accordion--label-1\">Startup grants<\/h2>\n\t\t\t\t\t\t\t\t\t\t\t<button type=\"button\" id=\"fl-accordion--icon-1\" aria-expanded=\"false\" aria-controls=\"fl-accordion--panel-1\"><i>Expand<\/i><\/button>\n\t\t\t\t\t<ul>\n<li>Grant available: up to \u00a340,000<\/li>\n<li>Funding period: maximum of two years, may be spread over a one- or two-year period.<\/li>\n<\/ul>\n\t\t\t\t\t<h2 id=\"fl-accordion--label-2\">Clinical training fellowships<\/h2>\n\t\t\t\t\t\t\t\t\t\t\t<button type=\"button\" id=\"fl-accordion--icon-2\" aria-expanded=\"false\" aria-controls=\"fl-accordion--panel-2\"><i>Expand<\/i><\/button>\n\t\t\t\t\t<ul>\n<li>Funding period: over 3 years maximum<\/li>\n<li>Items of expenditure: fellow&#8217;s salary, higher degree fees, and consumables<\/li>\n<li>Annual consumables allowance: \u00a315,000<\/li>\n<\/ul>\n\t\t\t\t\t<h2 id=\"fl-accordion--label-3\">Clinical PhD (AHP) fellowships (for allied health professionals and psychologists)<\/h2>\n\t\t\t\t\t\t\t\t\t\t\t<button type=\"button\" id=\"fl-accordion--icon-3\" aria-expanded=\"false\" aria-controls=\"fl-accordion--panel-3\"><i>Expand<\/i><\/button>\n\t\t\t\t\t<ul>\n<li>Funding period: over 3 years maximum<\/li>\n<li>Items of expenditure: fellow&#8217;s salary, higher degree fees, and consumables<\/li>\n<li>Annual consumables allowance: \u00a315,000<\/li>\n<\/ul>\n\t\t\t\t\t<h2 id=\"fl-accordion--label-4\">Senior non-clinical fellowships<\/h2>\n\t\t\t\t\t\t\t\t\t\t\t<button type=\"button\" id=\"fl-accordion--icon-4\" aria-expanded=\"false\" aria-controls=\"fl-accordion--panel-4\"><i>Expand<\/i><\/button>\n\t\t\t\t\t<ul>\n<li>Funding period: over 5 years maximum<\/li>\n<li>Items of expenditure: fellow&#8217;s salary and consumables<\/li>\n<li>Annual consumables allowance: \u00a324,000<\/li>\n<\/ul>\n\t\t\t\t\t<h2 id=\"fl-accordion--label-5\">Intermediate non-clinical fellowships<\/h2>\n\t\t\t\t\t\t\t\t\t\t\t<button type=\"button\" id=\"fl-accordion--icon-5\" aria-expanded=\"false\" aria-controls=\"fl-accordion--panel-5\"><i>Expand<\/i><\/button>\n\t\t\t\t\t<ul>\n<li>Funding period: over 3 years maximum<\/li>\n<li>Items of expenditure: fellow&#8217;s salary and consumables<\/li>\n<li>Annual consumables allowance: \u00a315,000<\/li>\n<\/ul>\n\t\t\t\t\t<h2 id=\"fl-accordion--label-6\">PhD studentships<\/h2>\n\t\t\t\t\t\t\t\t\t\t\t<button type=\"button\" id=\"fl-accordion--icon-6\" aria-expanded=\"false\" aria-controls=\"fl-accordion--panel-6\"><i>Expand<\/i><\/button>\n\t\t\t\t\t<ul>\n<li>Funding period: over 3 \u00bd years maximum<\/li>\n<li>Items of expenditure: student&#8217;s stipend, higher degree fees and consumables.<\/li>\n<li>Annual consumables allowance: \u00a35,000 up to a maximum of \u00a315,000.<\/li>\n<\/ul>\n\t<h2>Submitting an application<\/h2>\n<p>Information on eligibility, grant regulations and conditions, and opening and closing dates for submissions.<\/p>\n\t<p><strong>The application process for this grant is single full application.<\/strong><\/p>\n\t<p><strong>Create account or log in to our Grant Management system<\/strong><\/p>\n\t<p><strong>Submit full grant application<\/strong><\/p>\n\t<p><strong>We will review your submission and update your application status<\/strong><\/p>\n\t<h2 data-node=\"wf8ntmr6beo9\">Application info<\/h2>\n<p>All submissions through our first main grant round will be subject to expert review involving members of our college of experts and our experts by experience. Get more information about the <a href=\"https:\/\/www.kidneyresearchuk.org\/research\/information-for-researchers\/research-funding\/grant-application-process\/\">expert review process<\/a>.<\/p>\n<p>All lead applicants must be resident in the United Kingdom and the research must be led from a UK establishment.<\/p>\n<p>We particularly encourage paediatric trainees to begin with a translational research project focused on a rare kidney disease.<\/p>\n<p>One award from this round will be available for a project that aligns with the goals of the <a href=\"https:\/\/www.kidneyresearchuk.org\/research\/information-for-researchers\/rare-and-paediatric-kidney-diseases\/lifearc-centre\/\">Kidney research UK -LifeArc Centre for Rare Diseases<\/a>. To strengthen your application, we recommend an early conversation with Dr Louise Oni, the centre&#8217;s lead.<\/p>\n\t\t\t<a href=\"https:\/\/kidneyresearchuk.org\/wp-content\/uploads\/2023\/03\/Regulations-and-Conditions-202204.pdf\"  target=\"_self\">\n\t\t\t\t\t\t\tRegulations and conditions\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/www.kidneyresearchuk.org\/research\/information-for-researchers\/research-funding\/grant-application-process\/\"  target=\"_self\">\n\t\t\t\t\t\t\tApplication process information\n\t\t\t\t\t<\/a>\n<h2>\n\t\t\tApplication key dates\t<\/h2>\n\t\n\t<p><a href=\"https:\/\/www.kidneyresearchuk.org\/research-new\/information-for-researchers\/research-funding\/grant-application-process\/\">How to apply?<\/a><\/p>\n\t<h2>Got a question? Get in touch.<\/h2>\n\t<p>For advice and or any help please contact a member of our Research Operations Team:<\/p>\n\t\t<h3>Get our Research Roundup email<\/h3>\n\t\t<p>Hear about the latest opportunities for researchers &#8211; including funding opportunities, conferences, plus the latest research.<\/p>\n\t\t\t<a href=\"https:\/\/www.kidneyresearchuk.org\/research\/information-for-researchers\/sign-up-for-research-roundup\/\"  target=\"_self\">\n\t\t\t\t\t\t\tSign up to email\n\t\t\t\t\t<\/a>\n\n","protected":false},"excerpt":{"rendered":"<p>What would it mean to change the future for a child with a rare kidney disease, or an adult living with a hereditary condition that has shaped their life.<\/p>\n<p>We are offering funding opportunities for researchers dedicated to advancing the understanding, diagnosis and treatment of paediatric and rare kidney diseases. Help us drive forward progress for patients with the highest unmet needs.<\/p>\n","protected":false},"featured_media":0,"template":"","grant_categories":[426,384,427,415,380,413,381],"class_list":["post-157402","research_grants","type-research_grants","status-publish","hentry","grant_categories-clinical-phd-fellowships","grant_categories-clinical-training-fellowships","grant_categories-intermediate-non-clinical-fellowships","grant_categories-phd-studentships","grant_categories-research-project-grants","grant_categories-senior-non-clinical-fellowships","grant_categories-start-up-grants"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Paediatric, rare and hereditary kidney diseases - Kidney Research UK<\/title>\n<meta name=\"description\" content=\"Funding for researchers dedicated to advancing the understanding, diagnosis and treatment of paediatric and rare kidney diseases.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.kidneyresearchuk.org\/research-grants\/paediatric-rare-hereditary-kidney-diseases\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Paediatric, rare and hereditary kidney diseases - 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